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Research Areas
Cell Mechanics
Microphysiological Systems (MPS)
Cellular microenvironement is a dynamic space where cells interact with their surroundings, including the extracellular matrix (ECM), neighboring cells, and mechanical forces. These components directly influence cell behavior through biophysical and biochemical cues. For instance, the ECM composition and stiffness impact cell adhesion, migration, and differentiation. Our lab focuses on understanding these intricate mechanical interactions to advance regenerative medicine, cancer and drug testing. Also, the chromatin packaging holds the blueprint of life. During cellular senescence and aging, chromatin architecture undergoes significant changes. We explore how chromatin spatial organization influence gene expression, cell fate, senescence and also aim to delay aging-related effects.
We specialize in microfluidic devices, with a strong focus on developing cutting-edge organ-on-chip platforms and advanced microfluidic platforms for drug testing. We have successfully developed many organ-on-chip models such as placenta-on-chip, skin-on-chip etc. which can be used to understand intrinsic organ specific function or to model diseases but not limited to. These microfluidic devices serve as powerful alternatives to traditional animal testing and 2D cell culture methods within the pharmaceutical industry. By mimicking physiological conditions more accurately, our devices accelerate drug screening processes and enhance safety assessments.
For internship and queries mail to: iitbombay.mlab@gmail.com
(Only the applications sent to this mail id will be considered)
Latest Research Publications
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Femtosecond Laser Assisted Fabrication of Functionalized Micro/Nanostructured Chitosan Patterns for ECM Free Cellular Adhesion and Alignment of Human Mesenchymal Stem Cells; Tejas Yuvaraj Suryawanshi, Sweta Rani, Rohit Joshi, Rahul Kumar Das, Sumit Saxena, Abhijit Majumder, Shobha Shukla; Small; 2025
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A 3D microfluidic model for preclinical drug permeation studies: Advancing validation of skin-on-chip technology, Deepa Chaturvedi, Manish Gore, Shital Yadav, Abhijit Majumder, Ratnesh Jain, Prajakta Dandekar; Journal of Pharmaceutical and Biomedical Analysis, 2025
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Histone acetylation alters the nuclear morphology and architecture of human mesenchymal stem cells in a rigidity-dependent manner; Rohit Joshi, Darshan Shah, K. V. Venkatesha, Abhijit Majumder; Soft Matter; 2025
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Exploring the effect of dynamic deformation on the tight junctions of endothelial cells; D Jahagirdar, R Kumar, A Majumder; bioRxiv; 2025
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High-Fidelity Simulation of Cell Adhesion and Flow with Coarse Grain Modelling: A Numerical and Experimental Approach; Rajat Mishra, Devashree Jahagirdar, Saumya Jaiswal, Amit Arora, Abhijit Majumder; bioRxiv, 2025
Latest News
December - 2025
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MLab got selected for Bharat Innovates 2026 (First Round).​​
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Congratulations to Dr. Arpita Ghosh for future endevours as Assistant Professor in NITTE, Mangalore.​​​​
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Congratulations to Sourav for being featured in IIT Newsletter: Democratizing Drug Testing: Sourav Mukherjee's Triumphant Journey in 3D Spheroid Culture, Link
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 Bharat Innovates 2026National Basecamp |  3D Bioprinter Workshop 2025Glimpse of the workshop at MLab |  TechFest 2025Mechanomimic |
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 Farewell of Dr Arpita GhoshCongratulations for Faculty position at NITTE, Mangalore |  Farewell of Mo (Mohamed Patel) |  Farewell of Deb |
 Srinidhi (L) & Sourav (R)Best Poster (L) and Best Presenter award (R) in Researcg Scholar's Symposium 2025 |  Farewell of (L to R) Vidisha, Aditi, Sneha, Avinav, Eshira |  Birthday of Eshira and Vidisha |
 Farewell of Gayatri & Ninad |  Prof. Majumder's lecture to kids from all over India |  Devashree presenting her work at MPS World Summit |
 Akshada's work covered by IITB-outreach program |  WhatsApp Image 2024-08-30 at 13.34_edited |  Ketaki Defense |
 Screenshot 2024-08-30 133628 |  Dr. Jahagirdar and Mr. Roy receiving best poster award |  Prof. Majumder receiving the Research Excellence Award |
 Chromatin Condensation Delays hMSC Senescence |  Book Chapter on Micro and Nanostructures in Regenerative Medicine |