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Research Areas
Cell Mechanics
Microphysiological Systems (MPS)
Cellular microenvironement is a dynamic space where cells interact with their surroundings, including the extracellular matrix (ECM), neighboring cells, and mechanical forces. These components directly influence cell behavior through biophysical and biochemical cues. For instance, the ECM composition and stiffness impact cell adhesion, migration, and differentiation. Our lab focuses on understanding these intricate mechanical interactions to advance regenerative medicine, cancer and drug testing. Also, the chromatin packaging holds the blueprint of life. During cellular senescence and aging, chromatin architecture undergoes significant changes. We explore how chromatin spatial organization influence gene expression, cell fate, senescence and also aim to delay aging-related effects.
We specialize in microfluidic devices, with a strong focus on developing cutting-edge organ-on-chip platforms and advanced microfluidic platforms for drug testing. We have successfully developed many organ-on-chip models such as placenta-on-chip, skin-on-chip etc. which can be used to understand intrinsic organ specific function or to model diseases but not limited to. These microfluidic devices serve as powerful alternatives to traditional animal testing and 2D cell culture methods within the pharmaceutical industry. By mimicking physiological conditions more accurately, our devices accelerate drug screening processes and enhance safety assessments.
For internship and queries mail to: iitbombay.mlab@gmail.com
(Only the applications sent to this mail id will be considered)
Latest Research Publications
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A functional placenta-on-chip model for maternal–fetal transport; A Bhide, S Mukherjee, K Ghosh, A Majumder, D Modi; Biofabrication; 2026
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Shape, shrink, spheroid: a DIY high-throughput spheroid generation device; P Mogha, S Mukherjee, T Gangwar, D Roy, A Vichare, S Kulkarni, Vineet Sharma, Abhijit Majumder; Biofabrication; 2026
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Hypoxia-driven changes in nuclear morphology as a determinant of cell migration; PK Agarwala, R Joshi, A Majumder, S Kapoor; Biophysical Journal; 2026
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Synthetic melanin as a bioinspired antioxidant: Modulating oxidative stress from 2D skin models to human skin validation; MT Patel, AD Vichare, S Mukherjee, A Majumder, PG Oppenheimer; Biomedicine & Pharmacotherapy; 2026
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Differential Expression of LncRNA NEAT1 in 3D Tumoroids Compared to 2D Cultures Highlights Its Role in Glioblastoma Progression; A Ghosh, S R, MK Jolly, A Majumder; Macromolecular Bioscience; 2026​
Latest News
July - 2026
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Congratulations to Sourav Mukherjee for his latest publication "Shape, shrink, spheroid: a DIY high-throughput spheroid generation device" in Biofabrication. Read more
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June - 2026
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MLab organised Industry Day on Novel Alternative Models (NAMs) in Drug Discovery at IIT Bombay.
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Congratulations to Sourav Mukherjee for his latest publication "A functional placenta-on-chip model for maternal–fetal transport" in Biofabrication. Read more
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Congratulations to Dr. Rohit Joshi for his latest publication "Hypoxia-driven changes in nuclear morphology as a determinant of cell migration" in Biophysical Journal. Read more
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Congratulations to Mohamed Patel, Aditi Vichare and Sourav Mukherjee for their latest publication "Synthetic melanin as a bioinspired antioxidant: Modulating oxidative stress from 2D skin models to human skin validation" in Biomedicine & Pharmacotherapy. Read more​​
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April - 2026
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MLab showcased its work on Organ-on-chip technology in IInvenTiv 2026 at IIT(ISM) Dhanbad.
March - 2026
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Huge congratulations to the MLab team! MLab’s first startup, Organomic has been selected for the 2nd round of Bharat Innovates. ​
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Congratulations to Dr. Tejas Suryawanshi for successfully defending his PhD thesis.
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December - 2025​
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MLab got selected for Bharat Innovates 2026 (First Round).​​
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Congratulations to Dr. Arpita Ghosh for future endevours as Assistant Professor in NITTE, Mangalore.​​​​
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Congratulations to Sourav for being featured in IIT Newsletter: Democratizing Drug Testing: Sourav Mukherjee's Triumphant Journey in 3D Spheroid Culture, Link
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 Rahul's Convocation |  Placenta-on-Chip featured in The EconomicTimes |  Placenta-on-Chip featured in BBC Marathi |
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 Placenta-on-Chip was featured on The Hindu |  3D Glioblastoma Model was featured in Navarashtra |  Saumya presenting her work at Johns Hopkins Bloomberg School of Public Health, Baltimore, USAPoster "A Brain Tumor-on-a-Chip Model to Mimic Glioblastoma-Induced Blood–Brain Barrier Dysfunction at "The Summer Immersion 2026, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA. |
 Industry day, NAMsIIT Bombay brought together researchers, industry leaders, and innovators to discuss the future of drug discovery. |  Bharat Innovates 2026 (Round 2)IIT Bombay |  Bharat Innovates 2026National Basecamp |
 3D Bioprinter Workshop 2025Glimpse of the workshop at MLab |  TechFest 2025Mechanomimic |  Farewell of Dr Arpita GhoshCongratulations for Faculty position at NITTE, Mangalore |
 Farewell of Mo (Mohamed Patel) |  Farewell of Deb |  Srinidhi (L) & Sourav (R)Best Poster (L) and Best Presenter award (R) in Researcg Scholar's Symposium 2025 |
 Farewell of (L to R) Vidisha, Aditi, Sneha, Avinav, Eshira |  Birthday of Eshira and Vidisha |  Farewell of Gayatri & Ninad |
 Prof. Majumder's lecture to kids from all over India |  Devashree presenting her work at MPS World Summit |  Akshada's work covered by IITB-outreach program |
 Ketaki's Convocation |  Ketaki Defense |  Screenshot 2024-08-30 133628 |
 Dr. Jahagirdar and Mr. Roy receiving best poster award |  Prof. Majumder receiving the Research Excellence Award |  Chromatin Condensation Delays hMSC Senescence |
 Book Chapter on Micro and Nanostructures in Regenerative Medicine |